Virulence Of 1918 Influenza Virus



It always puzzled the scientists, why the pandemic flu in 1918 was so rampant and the virus was so virulent. The first comprehensive analysis of an animal's immune response to the 1918 influenza virus provides new insights into the killer flu, report federally supported researchers in an article appearing online today in the journal Nature. Key among these insights, they observed that the 1918 virus triggers a hyperactive immune response that may contribute to the lethality of the virus. Furthermore, their results suggest that it is the combination of all eight of the 1918 flu virus genes interacting synergistically that accounts for the exceptional virulence of this virus........
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